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Institute for Biomaterials
and Cell Therapy, IBCT
Medicinaregatan 8A
SE- 413 46 Göteborg Sweden
Phone: +46 (0)31 741 17 55
Fax: +46 (0)31 - 41 97 00

IBCT Scientific documentation
1. Individuals participating in IBCT projects who have performed a doctorate with one or more scientific publications as a result of the IBCT project:

Malmström, Johan, DDS (b. 750624): Institute for Clinical Sciences, Department of Biomaterials, Sahlgrenska Academyat University of Gothenburg  On bone regeneration in porous bioceramics. ISBN 978-91-628-7207-6, Göteborg, 2007-06-08. Faculty opponent Professor Fernando Monteiro, Portugal
 
Palmquist, Anders, MSc (b. 770531), Institute for Clinical Sciences, Department of Biomaterials, Sahlgrenska Academyat University of Gothenburg. On a novel technique for preparation and analysis of the implant surface and its interface to bone. ISBN 978-91-628-7504-6, Göteborg, 2008-06-04. Faculty opponent Dr Serena Best, Cambridge, UK

 
2. Scientific publications in the IBCT project (peer-reviewed journals):
 
Engqvist, H., Botton, G.A., Couillard, M., Mohammadi, S., Malmström, J., Emanuelsson, L., Hermansson, L., Phaneuf, M.W., Thomsen, P.: A novel tool for high-resolution transmission electron microscopy of intact interfaces between bone and metallic implants. J Biomed. Mater. Res A. Jul;78(1)20-24, 2006

Ellingsen, J.E., Thomsen, P. and Lyngstadaas, S.P.: Advances in dental implant materials and tissue regeneration. Periodontology 2000, Vol. 41, 136-156, 2006

Malmström, J., Adolfsson, E., Arvidsson, A., Thomsen, P.: Bone response inside free-form fabricated macroporous hydroxyapatite scaffolds with and without an open microporosity. Clin Implant Dent Relat Res 9(2), 79-88, 2007

Hermansson, L., Olaisson, E., Höglund, U., Thomsen, P., Engqvist, H.: Comparative study of the behaviour of a novel injectable bioceramic in sheep vertebrae. Trends in Biomaterials and artificial organs 22(3), 134-139, 2008

Malmström, J., Adolfsson, E., Emanuelsson, L., Thomsen, P. : Bone ingrowth in zirconia and hydroxyapatite scaffolds with identical macroporosity. J Mater Sci: Mater Med, 19, 2983-2992, 2008

Suska, F., Emanuelsson, L., Johansson, A., Tengvall, P., Thomsen, P.: Fibrous capsule formation around titanium and copper. J Biomed Mater Res A 85(4), 888-896, 2008

Engqvist, H., Svahn, F., Jarmar, T., Detsch, R., Mayr, H., Thomsen, P., Ziegler, G.: A novel method for producing electron transparent films of interfaces between cells and biomaterials. J. Mater Sci: Mater Medicine 19(1), 467-470, 2008

Jarmar, T., Palmquist, A., Brånemark, R., Hermansson, L., Engqvist, H., Thomsen, P.: Characterization of the surface properties of commercially available dental implants using scanning electron microscopy, focused ion beam, and high-resolution transmission electron microscopy. Clinical Implant Dentistry and Related Research 10(1), 11-22, 2008

Palmquist, A., Jarmar, T., Emanuelsson, L., Brånemark, R., Engqvist, H., Thomsen, P.: Forearm bone anchored amputation prosthesis: A case study on the osseointegration, Acta Orthopaedica 79(1), 75-85, 2008

Lindberg, F., Heinrichs, J., Ericson, F., Thomsen, P., Engqvist, H.: Hydroxylapatite growth on single-crystal rutile substrates. Biomaterials 29, 3317-3323, 2008

Heinrichs, J., Jarmar, T., Wiklund, U., Engqvist, H.: Physical vapour deposition and bioactivity of crystalline titanium dioxide thin films. Trends in Biomaterials and artificial organs 22(1), 100-106, 2008

Jarmar, T., Palmquist, A., Brånemark, R., Hermansson, L., Engqvist, H., Thomsen, P.: Technique for preparation and characterization in cross-section of oral titanium implant surfaces using focused ion beam and transmission electron microscopy, J Biomed Mater Res A 2008 Dec 15;87A(4):1003-1009.

Thomsen, P., Malmström, J., Emanuelsson, L., René, M., Snis, A. : Electron beam-melted, free-form-fabricated titanium alloy implants : material surface characterization and early bone response in rabbits. J Biomed Mater Res B, 2008 Nov 5 (Epub ahead of print)

Palmquist, A., Lindberg, F., Emanuelsson, L., Brånemark, R., Engqvist, H., Thomsen, P.: Morphological studies on machined implants of commercially pure titanium and titanium alloy (Ti6Al4V) in the rabbit. J Biomed Mater Res B2009, inpress
 
Palmquist A, Jarmar T, Hermansson L, Emanuelsson L, Taylor A, Taylor M, Engqvist, H., Thomsen, P.: Calcium aluminate coated and un-coated free form fabricated CoCr implants, a comparative study in rabbit. J Biomed Mater Res B2009, inpress

Palmquist, A., Lindberg, F., Emanuelsson, L., Brånemark, R., Engqvist, H., Thomsen, P.: Biomechanical, histological and ultrastructural analyses of laser micro- and nano-structured titanium alloy implants: A study in rabbit. J Biomed Mater Res A2009, inpress

Omar, O., Svensson, S., Zoric, N., Lennerås, M., Suska, F., Wigren, S., Hall, J., Nannmark, U., Thomsen, P.: In vivo gene expression in response to anodically oxidized versus machined titanium implants. J Biomed Mater Res A2009, inpress
 
Almqvist, S., Werthén, M., Johansson, A., Ågren, M., Thomsen, P.: Evaluation of a near-senescent human dermal fibroblast cell line and effect of amelogenin. Br J Dermatology,2009, inpress
 
Malmström, J., Slotte, C.,  Adolfsson, E., Norderyd, O., Thomsen, P.: Bone response to free form fabricated hydroxyapatite and zirconia scaffolds. A histological study in the human maxilla. Clinical Oral Implants Research,2009, inpress

Omar, O., Suska, F., Lennerås, M., Zoric, N., Svensson, S., Hall, J., Emanuelsson, L., Nannmark, U., Thomsen, P.: The influence of bone type on gene expression in normal bone and at the bone-implant interface: experiments in animal model. Clinical Implant Dentistry and Related Research,2009, inpress
 
Malmström, J., Jarmar, T., Adolfsson, E., Engqvist, H., Thomsen, P.: Structure of the interface between bone and scaffolds of zirconia and hydroxyapatite, Submitted for publication
 
Andersson, M., Almqvist, S., Stenhamre, H., Gretzer, C.: Ex vivo skin model for percutaneous implants, Submitted for publication

3. Scientific publications in the IBCT project (peer-reviewed conference abstracts):
 
Thomsen, P.: Overview of the techniques for preparation of the intact material-tissue interface. Abstract, Invited lecture, 6th Advanced Course in Cell-Material Interactions at Molecular Level, Instituto de Engenharia Biomedica (INEB) and Faculdade de Engenharia (FEUP), University of Porto, Portugal, 2005

Thomsen, P.: Early cell-material interactions in vivo. Abstract, Invited lecture, 6th Advanced Course in Cell-Material Interactions at Molecular Level, Instituto de Engenharia Biomedica (INEB) and Faculdade de Engenharia (FEUP), University of Porto, Portugal, 2005

Engqvist, H., Botton, G.A., Couillard, M., Mohammadi, S., Malmström, J., Emanuelsson, L., Hermansson, L, Phaneuf, M.W. and Thomsen, P.: Ultrastructural investigation of intact interfaces between metallic implants and bone. Abstract, European Society of Biomaterials, Sorrento ,Italy, 2005

Engqvist, H., Jarmar, T., Hermansson, L. and Thomsen, P.: Characterization of the tissue-bioceramic interface in vivo using new preparation and analytical tools. Abstract, Invited lecture, CIMTEC 2006, Italy, Advances in Science and Technology Vol 49, 2006, pp 275-281

Thomsen, P., Suska, F., Emanuelsson, L., Johansson, A., Jarmar, T. and Engqvist, H.: Preclinical in vivo models to study the inflammatory response to implants. Abstract, Invited lecture, CIMTEC 2006, Italy, Advances in Science and Technology Vol 49, 2006

Palmquist, A., Jarmar, T., Engqvist, H., Brånemark, R., Thomsen, P.: TEM sample preparation using focused ion beam microscopy applied on interfaces between tissue and implant material (Project Beta; Institute for Biomaterials and Cell Therapy) Biointerfaces Quo Vadis Göteborg, Sweden 2006

Hermansson, L., Jarmar, T., Engqvist, H.: Chemical aspects of bioactive injectable biomaterials based on chemically bonded ceramics. Biointerfaces Quo Vadis Göteborg, Sweden, 2006

Engqvist, H., Jarmar, T., Palmquist, A., Brånemark, R., Thomsen, P.: A novel TEM sample preparation method combined with high resolution analysis of the interface between tissue and implant material, Medicinteknikdagarna, Uppsala, Sweden, 2006

Jarmar, T., Malmström, J., Palmquist, A., Emanuelsson, L., Adolfsson, E., Brånemark, R., Engqvist, H., Thomsen, P.: High Resolution TEM Analysis of Interfaces between Biomaterials and Tissue. Abstract, European Society for Biomaterials, Nantes, 2006

Jarmar, T., Malmström, J., Palmquist, A., Emanuelsson, L., Brånemark, R., Thomsen, P., Engqvist, H.: Pioneering TEM sample preparation and analysis of the interface between tissue and implant material, Gordon  Conference on Biointerfaces ,Switzerland 2006

Adolfsson, E., Malmström, J., Thomsen, P.: Evaluation of bone growth in free formed fabricated scaffolds. Abstract, BIOCERAMICS 20, Nantes ,France, 2007

Engqvist, H., Palmquist, A., Lindberg, F., Jarmar, T., Brånemark, R., Emanuelsson, L., Thomsen, P.: Transmission electron microscopy of interfaces between hard tissue and biomaterials, ECM VIII, European Cells and Materials 14, 61, Switzerland 2007

Zoric, N., Omar, O.M., Suska, F., Svensson, S., Wigren, S., Hall, J., Nannmark, U, Thomsen, P.: Quantitative PCR: A promising technique investigating the early bone-implant interface. Abstract, European Association for Osseointegration, 16th Annual Scientific Meeting, Barcelona ,Spain, 2007

Palmquist, A., Jarmar, T., Lindberg, F., Engqvist, H., Brånemark, R., Thomsen, P.: Surface properties of dental implants using high-resolution transmission electron microscopy. Abstract, European Association for Osseointegration, 16th Annual Scientific Meeting, Barcelona ,Spain, 2007

Engqvist, H., Palmquist, A., Lindberg, F., Jarmar, T., Brånemark, R., Emanuelsson, L., Thomsen, P.: New method for preparation of ultrathin samples of the intact bone-implant interface for transmission electron microscopy analysis, MTF 2007,Örebro , Sweden

Slotte, C., Sjödin, S., Thomsen, P.: Time and spatially resolved detection of cells and gene expression in human implant-tissue interfaces using real-time PCR. Abstract, Odontologisk Riksstämma, Göteborg ,Sweden, November 2007

Slotte, C., Zoric, N., Göthberg, C., Nannmark, U., Suska, F., Thomsen, P.: Monitoring of some genes specific for inflammation and healing in peri-implant crevicular fluid after placement and loading of dental implants. A kinetic clinical pilot study of Quantitative Microarray Real-Time PCR.  Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Thomsen, P., Malmström, J., Emanuelsson, L., Snis, A., René, M.: Electron beam melted titanium: material characterization and bone response. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Palmquist, A., Brånemark, R., Thomsen, P.: Bone response to laser-induced micro- and nano-sized titanium surface features. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Palmquist, A., Johansson, A., Suska, F.,  Brånemark, R., Thomsen, P.: Acute inflammatory response to laser-induced micro- and nano-sized titanium surface features. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Palmquist, A., Jarmar, T., Emanuelsson, L., Brånemark, R., Engqvist, H., Thomsen, P.: Bone-anchored amputation prosthesis: Case study after 11 years of use. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Palmquist, A., Jarmar, T., Emanuelsson, L., Brånemark, R., Engqvist, H., Thomsen, P.: Comparison of embedding resins with regards to implant surface adhesion, an important factor for ultrastructural analysis. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Palmquist, A., Jarmar, T., Emanuelsson, L., Taylor, A., Taylor, M., Brånemark, R., Engqvist, H., Thomsen, P.: Calcium aluminate coated and non-coated free form fabricated CoCr implants, a comparative study in rabbit. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Palmquist, A., Jarmar, T., Malmström, J., Thomsen, P., Brånemark, R., Adolfsson, E., Engqvist, H.: FIB preparation of implant-tissue interfaces for ultrastructural analysis. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Ramstedt, S., Johansson, A., Palmquist, A., Breding, K., Engqvist, H., Thomsen, P.: Inflammatory response to injecable bone-filling materials. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Almqvist, S., Werthén, M., Johansson, A., Ågren, M.S., Thomsen, P.: In vitro effect of amelogenin on selected cell mediators from human monocytes. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Omar, O., Suska, F., Zoric, N., Lennerås, M., Svensson, S., Wigren, S., Hall, J., Nannmark, U., Thomsen, P.: The influence of bone type and sample size on the gene expression in bone. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Johansson, M., Edwin, B., Hultén, L., Axelsson, R., Fosse, E., Thomsen, P.: The healing process of an ileostomy to a percutaneous titanium implant: a short term experimental study on animals. Abstract, World Biomaterials Congress, Amsterdam, 2008
 
Thomsen, P., Engqvist, H., Lausmaa, J.: Biomaterials in Sweden. Abstract, 7th ScanBalt Forum and Biomaterials Days 2008, Vilnius, 24-26 September, 2008
 
Thomsen, P: Basic science, clinical and industrial perspectives on osseointegration. Abstract, 7th ScanBalt Forum and Biomaterials Days 2008, Vilnius, 24-26 September, 2008
 
Palmquist, A., Brånemark, R., Engqvist, H. et al: Bone bonding of surface modified implant materials analysed using FIB and high resolution TEM. Abstract, ScanBalt Forum and Biomaterials Days 2008, Vilnius, 24-26 September, 2008
 
Palmquist, A., Brånemark, R., Thomsen, P.: Preparation of TEM sample with FIB: A new tool for high resolution analysis of the intact bone-implant interface. Abstract, Medicinteknikdagarna MTF, Göteborg, 14-15 October, 2008
 
Almqvist, S., Kleinman, H., Werthén, M., Thomsen, P., Ågren, M.: Ex vivo study of the angiogenic effect of the extracellular matrix protein amelogenin. Abstract, 9th New JerseySymposium on biomaterials science and regenerative medicine, New Jersey, 29-31 October, 2008
 
Stegberg, E., Almqvist, S., Ågren, M, Werthén, M.: Amelogenin, an ECM protein restores chronic fibroblast vitality in a 3D in vitro model for dermal regeneration. Abstract, 9th New JerseySymposium on biomaterials science and regenerative medicine, New Jersey, 29-31 October, 2008
 
Palmquist, A., Lindberg, F., Emanuelsson, L. et al: Biomechanical, histological and ultrastructural analysis of micro- and nano-structured titanium alloy implants. Abstract, submitted, 55th Annual meeting, Orthopaedic Research Society, Las Vegas, 22-25 February, 2009
 
Palmquist, A., Lindberg, F., Emanuelsson, L. et al: Morphological studies on machined implants of commercially pure titanium and titanium alloy (Ti6Al4V). Abstract, submitted, 55th Annual meeting, Orthopaedic Research Society, Las Vegas, 22-25 February, 2009
 
Almquist, S., Werthén, M., Johansson, A., Ågren, M.S., Thomsen, P., Lyngstadaas, S.P.:
Effect of amelogenin on global gene expression and integrins in human dermal fibroblasts. Abstract, submitted, 22nd European Conference on Biomaterials, Lausanne, 7-11 September, 2009
 
Grandfield, K., Palmquist, A., Malmström, J., Emanuelsson, L., Slotte, C., Adolfsson, E., Botton, G.A., Thomsen, P., Engqvist, H.: Bone regeneration in hydroxyapatite scaffolds: an in-vivo study in humans. Abstract, submitted, 22nd European Conference on Biomaterials, Lausanne, 7-11 September, 2009
 
Omar, O., Svensson, S., Lennerås, M., Suska, F., Zoric, N., Emanuelsson, L., Hall, J., Nannmark, U., Thomsen, P.: Gene expression during early cellular recruitment and adhesion to titanium implants. Abstract, submitted, 22nd European Conference on Biomaterials, Lausanne, 7-11 September, 2009
 
Omar, O., Suska, F., Lennerås, M., Svensson, S., Emanuelsson, L., Hall, J., Nannmark, U., Thomsen, P.: The influence of bone type on the gene expression at the bone-implant interface. Abstract, submitted, 22nd European Conference on Biomaterials, Lausanne, 7-11 September, 2009
 
Palmquist, A., Emanuelsson, L., Brånemark, R., Thomsen, P.: Bone response to laser-induced
micro- and nano-sized titanium surface features: 6 months follow-up in rabbit. Abstract, submitted, 22nd European Conference on Biomaterials, Lausanne, 7-11 September, 2009
 

Updated: 2010-02-12
Anders Eriksson
Director, Institute for Biomaterials and Cell Therapy
Phone: +46 (0)31-741 17 55
Mobile: +46 (0)707-63 43 36
Peter Thomsen
Professor, MD, PhD
Scientific Leader, Institute for Biomaterials and Cell Therapy
Phone: +46 (0)31 741 17 55
Mobile: +46 (0)705 255 554
Jenny Mossberg
Project Coordinator, Institute for Biomaterials and Cell Therapy
Phone: +46 (0)31 741 17 55
Mobile: +46 (0)701 30 82 29
GöteborgBIO | Address: Medicinaregatan 8a | SE-413 46 Göteborg | Sweden | Fax: +46 31-41 97 00